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p < 0.001 on 10 million users, and still not worth shipping

Asked at Google

An experiment on 10 million users finds a 0.01% relative increase in clicks with p<0.001p < 0.001. The analyst reports it as a "highly significant win."

Explain why a tiny effect can be highly statistically significant, and how to distinguish statistical significance from practical significance.

Your answer

This one is open-ended. Work it through, then check your reasoning against the full solution.

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